Auto-Venting Pressure Equilibrium Vial Cover for Lyophilization

• Customization: Available
• Closure Type: Rubber Stopper
• Color: Customized
• Graduation: Without Graduation
• Material: Rubber
• Shape: Round
• Type: Storage Vial
• Usage: Biotechnology, Laboratory, Pharmaceuticals, Sample Storage
• Transport Package: Box

Product Description

Our gray rubber Auto-Venting Pressure Equilibrium Vial Cover is engineered to solve the most challenging pressure-related issues in lyophilization processes. Made from pharmaceutical-grade gray bromobutyl rubber , this innovative closure automatically regulates internal pressure during freeze-drying and storage through its precision-engineered venting channels.  


 

1. Smart Pressure Equalization     
• Self-activating venting at ±0.35 psi differential pressure 
• Prevents stopper displacement and vial breakage  
 

2. Lyophilization-Optimized Design     
• Maintains integrity during extreme temperature swings (-80°C to +120°C)  
• Gray color provides visual contrast for automated inspection  


3. Enhanced Drug Protection   
• Low extractables formulation (≤0.1%)  
• Compatible with biologics and sensitive formulations  
 


 

Material	Gray bromobutyl rubber (USP Class VI, EP 3.2.9)
Sizes	5mm
Sterilization	Validated for gamma/EO sterilization

 

Full technical support including:	Pressure equalization test reports
	Leachable/extractable data
	Process validation protocols

 

30% reduction in lyophilization failures vs standard closures  

Proven performance in 50+ biopharma applications